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Gwyer, D

Shechter et al

1 Introduction Hyperthyroidism is a common endocrine disorder characterized by excessive production and release of thyroid hormones, typically presenting with weight loss, palpitations, and fatigue

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The addition of glucagon receptor activation in retatrutide, combined with GIP, creates a metabolic environment that simultaneously improves insulin sensitivity, enhances appropriate insulin secretion, and increases energy expenditure